While topical creams claim to be the best way to achieve youthful, glowing skin, the most effective path to turning back the clock on skin health starts within, at the cellular level.
One molecule, often overlooked in skincare conversations, plays a pivotal role in cellular function and resilience: nicotinamide adenine dinucleotide, or as you may know it, NAD⁺. Backed by decades of biochemical and clinical research, NAD⁺ is emerging as one of the most promising allies in the science of skin rejuvenation.¹ Far beyond aesthetics, this coenzyme fuels the very processes that keep skin firm, luminous and healthy.
What is NAD⁺ & Why Does it Matter for Skin?
NAD⁺ is a critical coenzyme found in every cell of the body. It powers essential biological functions such as energy production, DNA repair, cellular detoxification and defense against oxidative stress.²,³ As we age, NAD⁺ levels decline, and skin loses its ability to bounce back from damage.³,⁴
Did You Know?
Low levels of NAD⁺ have been linked to visible signs of aging, such as dullness, fine lines and loss of elasticity.⁴,⁵
The Skin-Transforming Benefits of NAD⁺
1. Accelerate DNA Repair & Cellular Protection
Every day, skin cells are bombarded by environmental stressors from UV rays, pollution,l and toxins. NAD⁺ energizes enzymes like sirtuins and poly (ADP-ribose) polymerases (PARPs), which orchestrate cellular repair and maintain DNA integrity.¹,⁶ Clinical studies show that restoring NAD⁺ levels enhances the skin’s natural ability to repair itself, reducing DNA damage that contributes to wrinkles and discoloration.¹,⁶
2. Target Senescent Cells
As we age, senescent cells accumulate in the skin, and these cells are no longer functional but remain in the tissue, contributing to chronic inflammation and breakdown of collagen.⁷,⁸ NAD⁺ activates pathways that support the clearance of these aged cells and stimulate the production of fresh, healthy ones, renewing the skin at a foundational level.⁷,⁸
3. Energize Skin Cells With Mitochondrial Support
The skin’s ability to regenerate and repair depends on mitochondrial energy. NAD⁺ is essential for efficient mitochondrial function, helping skin cells perform their duties with greater vitality. The result? A complexion that looks brighter, firmer and more resilient.²,⁴
4. Preserve Collagen & Elasticity
Collagen and elastin are the architectural proteins that keep skin smooth, firm and supple. NAD⁺ not only supports their synthesis but also enhances autophagy, a cellular detox process that clears out damaged proteins and prevents glycation, a major contributor to sagging and texture changes.⁷,⁹
5. Shield Skin from Photoaging
UV exposure is one of the most aggressive accelerators of skin aging. Research indicates that NAD⁺ supplementation improves the skin’s defense mechanisms against sun-induced DNA damage, supports recovery and reduces inflammation post-exposure, making it a potent strategy for long-term skin preservation.¹,⁷
IV Drips & IM Shots
While NAD⁺ declines with age, these levels can be restored with IV Therapy and IM Shots, which deliver this essential molecule directly into the bloodstream or muscle. This route bypasses the digestive system, ensuring rapid cellular benefits.⁵ Clients often notice improvements in skin hydration, radiance, tone and elasticity, alongside enhanced overall energy and clarity.⁵
More Reasons to Invest in NAD⁺ Therapy
- Fast-Acting Absorption: IV and IM Shot delivery ensures NAD⁺ reaches target tissues quickly, optimizing its cellular impact.⁵
- Synergistic with Skincare Treatments: NAD⁺ enhances the results of microneedling, laser and other aesthetic procedures by accelerating healing and reducing inflammation.¹,⁷
- Total Body Benefits: NAD⁺ doesn’t just rejuvenate skin. It supports cognitive function, metabolic balance and immune resilience.²,³
The Bottom Line
Skin with that youthful glow isn’t just well-moisturized. It’s well-energized at the cellular level.
NAD⁺ is a scientifically validated, deeply restorative molecule that transforms skin health from the inside out.¹,² With NAD⁺ IV Drips or IM Shots, you can access this powerful, evidence-based solution to elevate your skin's vitality—and overall wellness—in a way that no topical cream ever could.
Ready to see the difference for yourself? Book your appointment today to get started.
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