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IV Therapy for Hormone Imbalance: A Smarter Way to Support Energy, Mood and Stress

Restore Hyper Wellness Writer
Written by:
Restore Hyper Wellness Writer
Reviewed by Restore Medical Team
Reviewed by:
Reviewed by Restore Medical Team
12 minute read
January 28, 2026
Woman gets IV Drip for hormone health I Restore Hyper Wellness
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Hormones are the unsung heroes of our bodies, working behind the scenes to keep everything in balance. These important chemical messengers are produced by glands and organs all over the body, from the thyroid to the ovaries. They play a key role in shaping our energy, mood, metabolism, sleep cycles and even how we age. 

Despite their importance and ubiquity, hormones can feel intimidating and mysterious. We don’t always understand how they shape our health or well-being, and we’re far from experts at keeping them in check.

The truth is, hormones don’t just kick in during our teenage years or perimenopause—they impact us every single day with the smallest of bodily functions. Learning how they work and understanding your unique hormonal profile are essential steps toward living your healthiest life. But where to start?

In this article, we’ll explore the science behind hormone imbalances, how they affect us and how getting the right nutrients can help support them. Our specially formulated IV Drip blends are designed by experts and backed by science to deliver these essential nutrients directly, supporting your hormones and helping you feel your best every day.

Highlights 

  • Hormone imbalance can cause a range of symptoms, including sleep issues, low mood and brain fog.
  • However, it can be difficult to pinpoint a hormone imbalance because they’re interconnected as part of the endocrine system, and symptoms can often be linked to multiple different things.
  • Hormones fluctuate throughout the day and across different life stages. It’s what helps our body function smoothly, manage stress and maintain overall balance.
  • IV Drip Therapy delivers essential nutrients that can support the body’s natural hormone production. 

What Is Hormone Imbalance, and Why Does It Feel So Hard to Manage?

Hormones aren’t fixed; they’re reactive, explains Chief Science Officer, Dr. Rachele Pojednic

“Hormones are designed to be responsive and reactive. You can think of them like a thermostat,” she explains. “When something changes—internally or externally—hormones rise or fall based on what your body needs in that moment.”

For women, they not only change in a monthly cycle, but across life stages such as pregnancy, postpartum, perimenopause and menopause. Men experience gradual hormonal changes too, particularly in testosterone.

Fluctuations are normal (and expected), but an imbalance occurs when your body has too much or too little of a particular hormone for an extended period. Having a hormone imbalance can cause many different symptoms, from sleep issues to mood changes. But finding the root cause of the symptoms can be tricky because hormones are all linked.

As hormones are part of the endocrine system—a complex network stretching across the entire body—they’re all interconnected and influence each other. Trying to pinpoint a specific hormone imbalance without tests is like trying to untangle a box of string lights or a necklace. You can’t work out where the tension is, and every time you make one breakthrough, you notice another knot further along the chain.

Why is IV Drip Therapy Better for Supporting Hormone Health

Once you understand your hormone imbalance, it’s only right that you want to address it as quickly and efficiently as possible. That’s why it’s important not only to understand your hormonal profile and select the right nutrients to support it, but to choose the most effective method of delivering those nutrients.

IV Drip Therapy can provide 100% nutrient absorption and offers a targeted, efficient way to support your hormonal health by delivering key nutrients directly into your bloodstream. This method ensures that your body gets the maximum benefit from each nutrient, helping to mitigate the effects of oxidative stress and support your natural hormone production processes.

By comparison, oral supplements must pass through the digestive system. Along the way, factors like gut health, medications and individual differences in metabolism can impact how much of the nutrient is actually absorbed. It is estimated that only 15-20% of nutrients actually reach the bloodstream.

‍Key IV Drip Nutrients That Support Hormone-Related Functions

Our IV Drips feature science-backed nutrients that support hormone balance and function. Paired with healthy lifestyle choices, such as quality sleep, nourishing food, regular exercise and stress reduction, they can help you feel ready to face whatever life throws at you.

Glutathione: The Guardian of Hormonal Balance

Imagine having a personal bodyguard who protects your cells from harm—that’s Glutathione, often called the "master antioxidant." This tiny but mighty molecule plays a crucial role in safeguarding your cells from oxidative stress, which happens when free radicals overwhelm your body’s antioxidants.1

As Glutathione plays a central role in antioxidant defense and cellular resilience, when levels drop, we can become more vulnerable to oxidative stress.2 Oxidative stress can impact hormone-producing glands, like the thyroid and reproductive organs, and has been linked to issues like polycystic ovary syndrome (PCOS).3 

Glutathione is a powerful antioxidant that helps your body detox and keeps your cells—including hormone receptors—healthy. 

Glutathione also helps regenerate other antioxidants, such as Vitamins C and E. In clinical studies, Vitamin E has been shown to help reduce the frequency and intensity of hot flashes for menopausal women.4

Think of Glutathione as your hormonal ally, working on multiple fronts to help support hormone balance.

B Vitamins (B2, B6 and B12): Your Behind-The-Scenes Buddies

B Vitamins play a key behind-the-scenes role in hormonal balance. B2, B6 and B12 work on a process called one-carbon metabolism, also known as methylation, which essentially helps to make and break down hormones, as well as keep them regulated.5

When B Vitamins are low, these processes might not work as well. This is why you might feel slightly foggy or sluggish. In fact, taking Vitamin B12 is associated with improved mood. B12 is vital for producing neurotransmitters like serotonin, dopamine and melatonin—the trio responsible for managing your mood, sleep and stress responses.5 

There is emerging evidence linking B Vitamins with hormone levels, too. In an observational study, Vitamin B2 was associated with lower estrogen levels, while Vitamin B12 was associated with higher testosterone levels.6 However, these numbers were small, and more research is needed to better understand the correlation.

B Vitamins (B6, B9, and B12) have also been linked to increased morning cortisol levels.7 This may be beneficial depending on your baseline levels, helping people to feel more awake and better able to handle daily stress. 

Preclinical studies suggest that B12 may help support adrenal and thyroid hormones.8 This evidence comes from animal models, so we don't have direct proof in humans yet. 

B Vitamins not only support hormonal pathways but can also help improve symptoms of hormone imbalance.

Vitamin C: The Stress Resilience Hero

You probably know Vitamin C as your immune system’s best friend, but did you know it also supports hormone production? Your adrenal glands, which are responsible for pumping out cortisol, aka ”the stress hormone”, contain high levels of Vitamin C and rely on it to function properly.9 Cortisol is essential for managing stress, and maintaining the right balance is key to keeping your mood and energy levels stable.

Vitamin C has been linked to higher progesterone levels and other reproductive hormones, suggesting it might support reproductive health.10

Ensuring your body has enough Vitamin C, especially during times of high stress or hormonal shifts, can help maintain your hormonal balance.

Magnesium: Your Relaxation Champion

Magnesium plays a supportive role in hormonal activity in the body. It helps manage stress hormones (like cortisol and adrenaline), break down estrogen (although indirectly) and support nervous system function, linking it to sleep and mood. Its roles might not be front and center, but it’s a behind-the-scenes player, keeping busy on a number of fronts.

Magnesium may prove particularly useful if a hormonal imbalance is causing sleep issues and undue stress. Maintaining optimal levels of Magnesium is linked to better-quality sleep (as it helps muscles relax) and lower anxiety. As hormonal changes can disrupt sleep, particularly during perimenopause and menopause, it might help support the natural sleep cycle.

‍Who May Benefit From Hormone Support Through IV Drip Therapy 

IV Drip Therapy may be particularly beneficial for those looking to support their hormonal health, especially if experiencing symptoms related to imbalance. Opting for IV Drip Therapy support might be particularly effective for those dealing with:

  • Chronic stress or burnout: B Vitamins, Magnesium and antioxidants like Vitamin C and Glutathione can help support adrenal function and resilience to stress.
  • Sleep issues or tiredness: Imbalances in cortisol and other hormones can disrupt sleep. B Vitamins, Magnesium and other nutrients can support the body for rest.
  • Perimenopause/menopause: Balancing nutrients can support the body through hormonal shifts such as perimenopause and menopause, easing symptoms related to sleep and anxiety.
  • Nutrient deficiencies, particularly with malabsorption conditions: By providing 100% bioavailability, IV Drip Therapy delivers directly to the bloodstream and can help replenish nutrients quickly. 
  • High-demand lifestyles, such as stress or travel: For those living life on the go, IV Drip Therapy offers an efficient way to maintain balanced nutrient levels and support hormone pathways.

Please note: Our wellness therapies are designed to complement a healthy lifestyle, not as a replacement for medication. 

What to Expect During IV Drip Therapy Sessions at Restore

Before your first session at Restore, you’ll fill out a health questionnaire and have a consultation with one of our medical professionals to discuss your wellness goals and any concerns. A Registered Nurse will take your vital signs before administering the Drip and monitor you throughout the session. 

We also offer a biomarker assessment to get a deeper understanding of your health by revealing your antioxidant, amino acid and micronutrient levels. This will help us create a wellness plan bespoke to your needs.

IV Drip Therapy nutrients are backed by peer-reviewed research and could be a valuable addition to your wellness routine, helping you maintain hormonal balance, boost your energy and keep your mood in check. Whether you’re looking to support your body through life’s inevitable stresses or simply want to feel more balanced, IV Drip Therapy may be just what you—and your hormones—need.

Book your IV Drip appointment today at one of our studios nationwide.

FAQs for IV Therapy for Hormone Imbalance

1. Why would a person need IV Drip Therapy?

IV Drip Therapy delivers nutrients directly into the bloodstream, providing fast, efficient delivery. This makes it ideal for people needing fast, efficient treatment. It can be accompanied by one of our biomarker assessments to assess which nutrients you may be deficient in. 

2. What is the best treatment for a hormonal imbalance?

There isn’t a single best treatment for hormone imbalance, rather a combination of different approaches to help manage your specific situation. Start by understanding what your hormone imbalance might be (either through a consultation or a test), and then use a combination of lifestyle factors and nutritional support to help you get back on the right track. What’s needed will depend on what’s imbalanced.

3. What is IV Therapy for hormonal balance?

There is no one-size-fits-all when it comes to the best IV Drip Therapy for hormonal balance. The most effective route is to support your body’s natural hormone production and regulation. At Restore, we recommend consulting with one of our medical professionals and having a biomarker assessment to help us to create a bespoke plan for your individual needs.

4. What are common signs of hormonal imbalance?

Having a hormone imbalance can cause many different symptoms, from sleep issues to mood changes. As our hormones are all interconnected across the endocrine system, it

can be tricky to pinpoint exactly what’s causing your symptoms. That’s why we recommend having a Biomarker Assessment to help understand your unique profile and wellness needs. Our Micronutrient & Antioxidant Assessment provides a clear picture of your cellular health by analyzing your antioxidant, amino acid and micronutrient levels.

5. How to reset hormonal imbalance?

Firstly, you need to understand (or test) your hormone levels. Then a combination of healthy lifestyle changes (think: better sleep, less stress) alongside a balanced, nutrient-rich diet and complementary wellness therapies, such as IV Drip Therapy.

Medical services are provided by an independently-owned physician practice. Some services may require medical clearance and a prescription. We reserve the right to refuse service to anyone. Services, therapies, ingredients and prices may vary per location. The content on our site, blog posts, educational materials, app, promotional newsletters and any other written content are not intended to replace an evaluation with a qualified healthcare professional and are not intended as medical advice.

Citations

  1. Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., Squadrito, F., Altavilla, D., & Bitto, A. (2017). Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity, 2017, 8416763. https://doi.org/10.1155/2017/8416763
  2. Detcheverry, F., Senthil, S., Narayanan, S., & Badhwar, A. (2023). Changes in levels of the antioxidant glutathione in brain and blood across the age span of healthy adults: A systematic review. NeuroImage: Clinical, 40, 103503. https://doi.org/10.1016/j.nicl.2023.103503
  3. ​​Li, W., Liu, C., Yang, Q., Zhou, Y., Liu, M., & Shan, H. (2022). Oxidative stress and antioxidant imbalance in ovulation disorder in patients with polycystic ovary syndrome. Frontiers in nutrition, 9, 1018674. https://doi.org/10.3389/fnut.2022.1018674
  4. Yousefi-Nodeh, H., Farshbaf-Khalili, A., Sadeghzadeh Oskouei, B., Jafarilar-Aghdam, N., Kazemi-Zanjani, N., & Pourzeinali, S. (2024). Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women: A triple-blind placebo-controlled clinical trial. Health Care for Women International, 45(11), 1184–1206. https://doi.org/10.1080/07399332.2022.2117815
  5. Kennedy D. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients, 8(2), 68. https://doi.org/10.3390/nu8020068
  6. Kim, K., Mills, J. L., Michels, K. A., Chaljub, E. N., Wactawski-Wende, J., Plowden, T. C., & Mumford, S. L. (2020). Dietary Intakes of Vitamin B-2 (Riboflavin), Vitamin B-6, and Vitamin B-12 and Ovarian Cycle Function among Premenopausal Women. Journal of the Academy of Nutrition and Dietetics, 120(5), 885–892. https://doi.org/10.1016/j.jand.2019.10.013
  7. Camfield, D. A., Wetherell, M. A., Scholey, A. B., Cox, K. H., Fogg, E., White, D. J., Sarris, J., Kras, M., Stough, C., Sali, A., & Pipingas, A. (2013). The effects of multivitamin supplementation on diurnal cortisol secretion and perceived stress. Nutrients, 5(11), 4429–4450. https://doi.org/10.3390/nu5114429
  8. Ajeel, M. T., Saleh, H. S., Din, A. M., Alashkham, F., & Said, R. M. (2025). Efficacy of vitamin B12 treatment on the adrenal gland of propylthiouracil-induced hypothyroid rats. Open Veterinary Journal, 15(6), 2395–2407. https://doi.org/10.5455/OVJ.2025.v15.i6.12
  9. Patak, P., Willenberg, H. S., & Bornstein, S. R. (2004). Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla. Endocrine research, 30(4), 871–875. https://doi.org/10.1081/erc-200044126
  10. Mumford, S. L., Browne, R. W., Schliep, K. C., Schmelzer, J., Plowden, T. C., Michels, K. A., Sjaarda, L. A., Zarek, S. M., Perkins, N. J., Messer, L. C., Radin, R. G., Wactawski-Wende, J., & Schisterman, E. F. (2016). Serum Antioxidants Are Associated with Serum Reproductive Hormones and Ovulation among Healthy Women. The Journal of nutrition, 146(1), 98–106. https://doi.org/10.3945/jn.115.217620

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